BUMEX Brand of bumetanide TABLETS
ثبت نشده
چکیده
DESCRIPTION Bumex (bumetanide) is a loop diuretic available as 0.5 mg (light green), 1 mg (yellow) and 2 mg (peach) tablets for oral administration; each tablet also contains anhydrous lactose, magnesium stearate, microcrystalline cellulose, pregelatinized starch and talc, with the following dye systems: 0.5 mg—D&C Yellow No. 10 aluminum lake and FD&C Blue No. 1 aluminum lake; 1 mg—D&C Yellow No. 10 aluminum lake; 2 mg— red iron oxide.
منابع مشابه
Inhibition of the Sodium-Potassium-Chloride Cotransporter Isoform-1 reduces glioma invasion.
Malignant gliomas metastasize throughout the brain by infiltrative cell migration into peritumoral areas. Invading cells undergo profound changes in cell shape and volume as they navigate extracellular spaces along blood vessels and white matter tracts. Volume changes are aided by the concerted release of osmotically active ions, most notably K(+) and Cl(-). Their efflux through ion channels al...
متن کاملInhibition of NKCC1 Attenuated Hippocampal LTP Formation and Inhibitory Avoidance in Rat
The loop diuretic bumetanide (Bumex) is thought to have antiepileptic properties via modulate GABAA mediated signaling through their antagonism of cation-chloride cotransporters. Given that loop diuretics may act as antiepileptic drugs that modulate GABAergic signaling, we sought to investigate whether they also affect hippocampal function. The current study was performed to evaluate the possib...
متن کاملEffectiveness of Bumetanide Infusion in Treatment of Generalized Edema and Congestive Heart Failure
Generalized edema (anasarca) is common in nephrotic syndrome which rarely produces shortness of breath. Increased shortness of breath associated with rapid weight gain and generalized edema signify congestive heart failure (CHF). Loop diuretics consisting of furosemide (Lasix®), bumetanide (Bumex®), torsemide (Demadex®) or ethacrynic acid (Edecrin) are effective diuretics to treat anasarca. How...
متن کاملLoop Diuretics Have Anxiolytic Effects in Rat Models of Conditioned Anxiety
A number of antiepileptic medications that modulate GABA(A) mediated synaptic transmission are anxiolytic. The loop diuretics furosemide (Lasix) and bumetanide (Bumex) are thought to have antiepileptic properties. These drugs also modulate GABA(A) mediated signalling through their antagonism of cation-chloride cotransporters. Given that loop diuretics may act as antiepileptic drugs that modulat...
متن کاملImpact of brand or generic labeling on medication effectiveness and side effects.
OBJECTIVE Branding medication with a known pharmaceutical company name or product name bestows on the drug an added assurance of authenticity and effectiveness compared to a generic preparation. This study examined the impact of brand name and generic labeling on medication effectiveness and side effects. METHOD 87 undergraduate students with frequent headaches took part in the study. Using a...
متن کامل